Information for the Lay Person

The primary focus of my research is to identify and evaluate the functional significance of cell-cell adhesion molecules known as cadherins, catenins in normal development and cancer progression. Our research is also aimed to understand the regulation of cadherin/catenin complex activity by Protein Kinase D signaling. In addition we are in process of investing how MUC13 mucin plays a role in abruption of cell-cell adhesion assembly in cancer cells. In-depth knowledge of molecular mechanisms involved in signal transduction of human cancers is critical for development of biomarker for early detection of cancer and rational and structure-based drug designing.