Research Support

LVZ113350

Effects of Lovaza on Lipoprotein structure and Function in mild hypertriglyceridemia (ELLF)

Evaluate the effects of prescription omega-3 administration on lipoprotein lipid, oxylipin and apolipoprotein content as well as changes in lipoprotein binding affinity in subjects on statins with mild hypertriglyceridemia.

May 2009 – April 2011. Sponsor: GlaxoSmithKline. Clinical Trial.gov: NCT00959842

LVZ112860

Effect of Lovaza on lipoprotein structure and in normolipidemics and in metabolic syndrome

In an ancillary study of the LONIA trial, evaluate the effects of prescription omega-3 administration on lipoprotein lipid, oxylipin and apolipoprotein content as well as changes in lipoprotein binding affinity in subjects on statins with metabolic syndrome.

May 2009 – April 2011. Sponsor: GlaxoSmithKline.

COBRE (7P20RR017662-07)

Role of lipoproteins in the transport and action of oxylipins Here, synthesis of lipoprotein-oxylipins by the isolated perfused liver is measured using tracer-labeled FAs. The impact of these oxylipins will be assessed on cell function.

Jan 2010 – Jun 2012. Sponsor: NIH.