Publications

PRIMARY ARTICLES

Surendran K, Selassie M, Liapis H, Krigman H, Kopan R. Reduced Notch signaling leads to renal cysts and papillary microadenomas. J Am Soc Nephrol. 2010 May;21(5):819-32. 

Surendran K, Boyle S, Barak H, Kim M, Stomberski C, McBright B, Kopan R. The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage. Developmental Biology. 2010 Jan;337(2):386-95.

Lin CL, Wang JY, Ko JY, Surendran K, Huang YT, Kuo YH, Wang FS. Superoxide destabilization of beta-catenin augments apoptosis of high-glucose-stressed mesangial cells. Endocrinology. 2008 Jun;149(6):2934-42.

Cheng HT, Kim M, Valerius MT, Surendran K, Schuster-Gossler K, Gossler A, McMahon AP, Kopan R. Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron. Development. 2007 Feb;134(4):801-11. 

Lin CL, Wang JY, Huang YT, Kuo YH, Surendran K, Wang FS. Wnt/beta-catenin signaling modulates survival of high glucose-stressed mesangial cells. J Am Soc Nephrol. 2006 Oct;17(10):2812-20.

Surendran K, Schiavi S, Hruska KA. Wnt-dependent beta-Catenin signaling is activated after unilateral ureteral obstruction, and recombinant Secreted Frizzled-Related Protein 4 alters the progression of renal fibrosis. J Am Soc Nephrol. 2005 Aug;16(8):2373-84.

Surendran K, Simon TC, Liapis H, McGuire JK. Matrilysin (MMP-7) expression in renal Tubular damage: Association with Wnt4. Kidney Int. 2004 Jun;65(6):2212-22.

Surendran K, Simon TC. CNP gene expression is activated by Wnt signaling and correlates with Wnt4 expression during renal injury. American Journal of Physiol. Renal Physiol. 2003 Apr;284(4):F653-F662.

Surendran K, McCaul SP, Simon TC. A role for Wnt-4 in renal fibrosis. American Journal of Physiol. Renal Physiol. 2002 Mar;282(3):F431-F441.

 
REVIEWS  
 

Surendran K and Kopan R. Chromatin mediated mechanisms of epithelial differentiation. J Am Soc Nephrol. 2011 Jul;22(7):1208-12. http://www.ncbi.nlm.nih.gov/pubmed/21700830

 

Kopan R, Cheng HT, Surendran K. Molecular Insights into Segmentation along the Proximal-Distal Axis of the Nephron, J Am Soc Nephrol. 2007 18(7):2014-20. http://www.ncbi.nlm.nih.gov/pubmed/17568016

Li T, Surendran K, Zawaideh MA, Mathew S, Hruska KA. BMP-7: a novel treatment for chronic renal and bone disease. Curr Opin Nephrol Hypertens. 2004 Jul;13(4):417-22.  http://www.ncbi.nlm.nih.gov/pubmed/15199292

Hruska KA, Saab G, Chaudhary LR, Quinn CO, Lund RJ, and Surendran K. Kidney-bone, bone-kidney, and cell-cell communications in renal osteodystrophy. Semin Nephrol. 2004 Jan;24(1):25-38. http://www.ncbi.nlm.nih.gov/pubmed/14730507

BOOK CHAPTER

Barak H, Surendran K, Boyle S.

The Role of Notch Signaling in Kidney Development and Disease.  Book chapter in: Notch Signaling in Embryology and Cancer. Edited by: Reichrath J and Reichrath S. Published by Landes Bioscience and Springer (2010).

http://www.landesbioscience.com/books/special/id/3706/